Figure 2.
Carotid β-stiffness (β-stiffness) of each fitness group and genotype of MTHFR gene polymorphism (C677T; CC, CT, TT genotypes) of 763 subjects in a cross-sectional study. Subjects were divided into low cardiorespiratory fitness (Low-Fit) and high cardiorespiratory fitness (High-Fit) groups, with the dividing line set at the median value of peak oxygen uptake in each sex and decade of age as a cutoff. Differences in β-stiffness between each fitness group and genotype were assessed by an analysis of covariance (ANCOVA) model that included age as a covariate. Data are expressed as means ± SE for numbers of subjects indicated in the bar. AU, arbitrary units; NS, not significant.
From Iemitsu M, Murakami H, Sanada K, et al. Lack of carotid stiffening associated with MTHFR 677TT genotype in cardiorespiratory fit adults. Physiol Genomics. 2010;42:259–65. Used with permission of the American Physiological Society.