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. Author manuscript; available in PMC: 2014 Mar 13.
Published in final edited form as: Med Sci Sports Exerc. 2011 May;43(5):743–752. doi: 10.1249/MSS.0b013e3182155d21

Figure 3.

Figure 3

Figure 3

Panel A. Number of subjects needed for a given effect size for a continuous trait assuming 80% statistical power, an additive model, and three alpha levels: 0.05 (1 SNP), 0.0001 (500 SNPs), and 5×10−8 (1 million SNP GWAS).

Panel B. Number of subjects needed for a given effect size (measured as an odds ratio [OR]) for a case-control design assuming 80% statistical power, a minor allele frequency (MAF) of 20%, an additive model, and three alpha levels: 0.05 (1 SNP), 0.0001 (500 SNPs), and 5×10−8 (1 million SNP GWAS).