Figure 3. Magnitude of the responses detected by the two different assays.
After five hours of stimulation with DMSO (top row), Env peptide pool (middle row) or Gag peptide pool (bottom row), the responses from 20 HIV-positive individuals were evaluated for CD4+ T cells (IFNγ and TNFα) and for CD8+ T cells (IFNγ and CD107a). Individual plots show the frequency of cytokine producing/degranulating cells detected by viral and standard ICS. The Wilcoxon signed-rank test was used to generate p values as reported in the figure.