Skip to main content

View full-text article in PMC

. Author manuscript; available in PMC: 2015 Apr 1.

Published in final edited form as: J Virol Methods. 2014 Jan 10;199:17–24. doi: 10.1016/j.jviromet.2014.01.003

Table 4. Magnitude of the CD8+ T cell responses by viral and standard ICS.

Medians and IQR were calculated for the frequencies of CD8+ T cells secreting both IFN-γ and TNF-α or only one of either cytokine.

	Stim	Median (IQR)		Wilcoxon signed rank p value
	Stim	Viral ICS	Traditional ICS	Wilcoxon signed rank p value
IFNγ/CD107a	DMSO	0.0030 (0.0000, 0.0120)	0.0000 (0.0000, 0.0100)	0.0448
	Env	0.0180 (0.0000, 0.1940)	0.0100 (0.0000, 0.1600)	0.6742
	Gag	0.0160 (0.0020, 0.8040)	0.0100 (0.0000, 0.1600)	0.5459
IFNγ	DMSO	0.8270 (0.5340, 1.2500)	0.2340 (0.1070, 0.5190)	<.0001
	Env	1.0130 (0.5800, 1.7680)	0.4280 (0.2480, 0.8460)	<.0001
	Gag	1.2850 (0.6530, 2.7810)	0.7330 (0.1930, 1.6390)	0.114
CD107a	DMSO	0.0090 (0.0030, 0.0300)	0.0150 (0.0060, 0.0360)	0.5949
	Env	0.0390 (0.0050, 0.2750)	0.0260 (0.0040, 0.2120)	0.2455
	Gag	0.0660 (0.0060, 0.9940)	0.0540 (0.0090, 1.4300)	0.0532