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. Author manuscript; available in PMC: 2014 Mar 13.
Published in final edited form as: Circulation. 2004 Sep 7;110(10):1180–1182. doi: 10.1161/01.CIR.0000140722.85490.EA

graphic file with name nihms332115f1.jpg

Important cellular pathways involved in development of aortic valve calcification, with potential targets for drug therapy outlined in red. ACEI indicates ACE inhibitor.