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. Author manuscript; available in PMC: 2014 Mar 13.
Published in final edited form as: Circulation. 2002 Jun 4;105(22):2660–2665. doi: 10.1161/01.cir.0000017435.87463.72

Plasma Cholesterol and hsCRP Levels, PCNA Quantification, and Osteoblast Markers in the Rabbit Treatment Groups.

Group I Control Group II
High-Cholesterol
Diet
Group III
High-Cholesterol Diet+Atorvastatin
Total cholesterol, mg/dL 50.7±12.4 3235±328.8* 1943±17.3
PCNA quantification (% area) 4.4±3.4 82.8±7.3* 21.9±10.1
hsCRP, mg/dL 0.039±0.004 0.16±0.13* 0.093±0.05
Alkaline phosphatase (RT-PCR) (475 bp) 1.8±3.12 3.6±1.3 0.21±0.37
Osteopontin (RT-PCR) (347 bp) 2.77±0.92 6.40±2.25* 3.43±0.91
Cbfa-1 (RT-PCR) (289 bp) 1.62±0.36 3.90±1.28* 2.30±0.71
*

P<0.001 compared with control,

P<0.001 compared with high-cholesterol diet.