Table IV.

Univariate analysis for overall survival

Variable	n/N (%)	Hazard Ratio	95% CI	p-value
At diagnosis
Age ≥ 60	24/65 (37%)	1.60	0.88-2.92	0.13
Male gender	41/65 (63%)	0.95	0.52-1.71	0.85
Caucasian	51/65 (78%)	1.41	0.70-2.84	0.34
ISS stage III	13/46 (28%)	2.99	1.42-6.32	0.004
At T0
Age ≥ 60	38/65 (58%)	1.09	0.61-1.95	0.77
Advanced lytic lesions	47/65 (42%)	2.30	1.13-4.69	0.02
Hemoglobin (per unit increase)	-	0.79	0.65-0.95	0.01
Albumin (per unit increase)	-	0.48	0.27-0.85	0.01
Elevated free light chains	26/53 (49%)	2.12	1.10-4.06	0.02
VRD prior to T0	20/65 (31%)	1.96	1.07-3.61	0.03

Abbreviations: CI- confidence interval; ISS- International Staging System; VRD- bortezomib.