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Reduction of endogenous RasGRP3 expression inhibited tumor formation of M14 cell lines.
| Cell Line (M14) | Total tumor/Total injection | Tumor weight (mg) | ||
|---|---|---|---|---|
|
| ||||
| Deoxytetracycline | Deoxytetracycline | |||
| − | + | − | + | |
| Control | 14/20 | 14/20 | 6.5±1.2 | 7.5±1.4 |
| sh854 | 12/20 | 10/20 | 8.1±2.5 | 2.9±0.8 |
