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. Author manuscript; available in PMC: 2015 Mar 15.
Published in final edited form as: J Neuroimmunol. 2014 Jan 15;268(0):50–57. doi: 10.1016/j.jneuroim.2014.01.002

Figure 1. LT-IS patches significantly increased humoral immune responses in C57BL/6 (A,C,E) and 12–16 month-old 3xTg-AD mice (B,D,F) immunized with DepVac administered intradermally via gene gun.

Figure 1

Concentrations of anti-Aβ antibodies were measured in individual mice after the 3rd immunization (A, B). Kinetics of anti-Aβ responses were analyzed in pooled sera (C, D). The isotypes of serum antibodies were analyzed in individual mice (E, F). Sera from wild-type and 3xTg-AD animals were used at dilutions of 1:500 and 1:200, respectively. Lines and error bars represent the average value ± SD.