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. Author manuscript; available in PMC: 2014 Jul 24.
Published in final edited form as: Neuron. 2013 Jun 27;79(2):361–374. doi: 10.1016/j.neuron.2013.05.038

Figure 8. Optogenetic Perturbation of IL Cortex Blocks Habit Formation.

Figure 8

(A) Light delivery, related to IL activity, from run start to stop, for 10 OT days only (stages 7–11). Box demarcates time of IL illumination.

(B) Performance accuracy during last 5 Acq sessions and 10 OT sessions. No effect of light on performance: session (F = 4.80, p < 0.001; group, F = 2.82, p = 0.10; interaction, F = 0.63, p = 0.84).

(C) Correct turns to devalued goal on last OT day with IL light and on post-devaluation probe day without light. Group, F = 44.80, p < 0.001; session, F = 21.12, p < 0.001; interaction, F = 14.44, p < 0.01. Interaction of goal value and group on probe day: F = 18.46, p < 0.001. ***p < 0.001 post-hoc. All other comparisons p > 0.05. Red dot = normal CT devaluation-sensitive behavior from Figure 1; blue = normal OT devaluation-insensitive behavior. Right, behavior during PP days.

(D) Correct runs to non-devalued goal, which did not change (group, F = 0.52, p = 0.48; session, F = 3.51, p = 0.078; interaction, F = 0.23, p = 0.64).