A) Regressing LSAS change (ΔPreTx - PostTx) while initial severity (LSASPreTx) is controlled for as a regressor of no interest; brain map depicts whole-brain analysis of covariance showing increased medial orbitofrontal gyrus reactivity to fearful faces in gSAD displayed on statistical t-map at p<0.001. B) Scatter plot of the regression analyses depicting extracted parameter estimates of activation from medial orbitofrontal region of interest showing greater response to CBT in gSAD is predicted by greater medial orbitofrontal gyrus reactivity to fearful faces.
LSAS, Liebowitz Social Anxiety Scale; CBT, Cognitive Behavioral Therapy; gSAD, Generalized Social Anxiety Disorder.