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. Author manuscript; available in PMC: 2015 Feb 1.
Published in final edited form as: Am J Obstet Gynecol. 2013 Sep 20;210(2):154.e1–154.e8. doi: 10.1016/j.ajog.2013.09.030

Figure 2.

Figure 2

Knockdown of ANTXR2 in HUSMC (HUSMC-R2KD) decreased directed cell migration whereas over-expression of ANTXR2 in HUSMC (HUSMC-R2OE) increased directed cell migration. A) Images of HUSMC-R2KD, control (HUSMC-CTL) and HUSMC-OE migrating cells on the lower surface of the Boyden chamber migration assay membrane. Cells are stained with crystal violet and pictures were obtained at 10X. B) HUSMC-R2KD cells migrated to PDGF-B to a lesser extent than HUSMC-CTL cells (p<0.05) indicating that ANTXR2 expression is necessary for chemokine-directed migration. HUSMC-R2OE cells exhibited increased migration relative to CTL (p=0.05).