Fig. 1.

Vaccine-elicited T cells that protect mice from tumor challenge produce multiple cytokines. a BALB/c mice were immunized with two different vaccines, which elicit antigen-specific CD8+ T cells that protect mice (protective) from tumor challenge or do not (non-protective). Splenocytes were isolated from mice and stimulated with antigen for 5 h in the presence of monensin. Cells were then stained with antibodies specific for cytokines IFNγ, TNFα, and IL-2. b Combined data plotted from a. *** p < 0.001