Table 2.
Clinical features of EoE cases
| EoE cases* (n = 16,405) | |
|---|---|
| Symptoms and diagnoses (n, %) | |
| Dysphagia | 9,147 (55.8) |
| Esophageal foreign body | 2,043 (12.5) |
| Esophageal stricture | 4,709 (28.7) |
| Esophageal web/congenital stenosis | 846 (5.2) |
| Esophageal perforation | 67 (0.4) |
| Abdominal pain/dyspepsia | 7,686 (46.9) |
| Heartburn | 1,448 (8.8) |
| Pain in chest or throat | 4,669 (28.4) |
| Nausea or vomiting | 4,253 (25.9) |
| Failure to thrive | 516 (3.1) |
| Allergic diseases (n, %) | |
| Any allergic disease | 8,663 (52.8) |
| Rhinitis | 6,850 (41.8) |
| Sinusitis | 2,493 (15.2) |
| Dermatitis | 1,418 (8.6) |
| Urticaria | 297 (1.8) |
| Asthma | 3841 (23.4) |
| Food allergies | 771 (4.7) |
| Medications (n, %)† | |
| H2 receptor blockers | 459 (3.7) |
| Proton-pump inhibitors | 6,467 (52.2) |
| Systemic corticosteroids | 3,498 (28.2) |
| Steroid preparation that could be used topically‡ | 1,431 (11.5) |
| Anti-histamines# | 1,300 (10.5) |
| Leukotriene antagonists** | 1,488 (12.0) |
*
Patients with at least one or more instance of an ICD-9 claim for 530.13 between 2008-2011
†
Medication data derived from 12,390 EoE subjects with a pharmacy drug benefit
‡
The asthma or nasal preparations of fluticasone, budesonide, beclomethasone, mometasone, ciclesonide, or flunisolide
#
Loratadine, desloratadine, fexofenadine, cetirizine, or levocetirizine
**
Montelukast, zafirlukast, or zileuton
Data source: IMS LifeLink® PharMetrics Health Plan Claims Database, January 2001-November 2011, IMS Health Incorporated. All Rights Reserved.