Table 3.
Phenowiki fields
| Field | Brief field description | Examples |
|---|---|---|
| Paper ID | ||
| *PMID | Hypertext link of the ID no. to national PubMed database | 17555989 |
| First author | First author’s last name | Bilder |
| Year | Year published | 2004 |
| Task ID | ||
| Cognitive domain | Latent construct defined in the manuscript | Working memory |
| Task | Name of behavioral task employed | N-back |
| Task version | If not a novel design, provide reference paper | Cohen 1997 |
| Sample characteristics (1→n)a | ||
| *Sample group | Who was run in the study (clinical/age/etc.) | SCZ or children or healthy |
| *Study design | (case–control, family, healthy, meta-analysis, twin) | Case–Control |
| *Female (%) | Percentage of females in the sample | 50 |
| *Mean age | Average age of participants in the sample | 50 |
| *Sample size | Number of participants in this sample | 50 |
| Metric characteristics (1→n)a | ||
| *Condition/contrast | Condition or comparison used to generate the stat value | 3-Back accuracy |
| *Cognitive metric | Statistical test parameter | F |
| Group 1 | First comparison group | Patients |
| Group 2 (if applicable) | Second comparison group | Controls |
| *Metric statistical value | Value of metric obtained from testing | 7.52 |
| 95% CI Min | Lower boundary of 95% confidence interval | 3.5 |
| 95% CI Max | Upper boundary of 95% confidence interval | 7.2 |
| Group 1 Mean | Average value for group 1 | 0.48 |
| Group 1 SD | Standard Deviation for group 1 | 0.25 |
| Group 2 Mean | Average value for group 2 | 0.78 |
| Group 2 SD | Standard Deviation for group 2 | 0.15 |
| P-value significance | Two-tailed significance value | 0.001 |
| Genetic validity (1→n)a | ||
| MZ ICC | Intraclass correlation coefficient for monozygotic twins | 0.47 |
| DZ ICC | Intraclass correlation coefficient for dizygotic twins | 0.2 |
| Heredity modeling package | N/A, Falconer’s h2, LISREL, MX, SOLAR | MX |
| Best fitting heritability model | Description of best fitting model | ACE |
| Heritability statistical value | Value for heritability statistic | 0.55 |
| Psychometric validity (1→n)a | ||
| Test–retest metric | Measure used to establish test–retest reliability | r |
| Test–retest statistic | Test–retest reliability value | 0.85 |
| Internal consistency | Coefficient α | 0.9 |
| Neural systems validity (1→n)a | ||
| Brain region of interest | Region tested | Inferior frontal gyrus |
| Spatial extent (voxels) | Spatial extent of that region, if defined functionally | 50 |
| Spatial smoothing kernel (mm) | Smoothing kernel used during pre-processing | 8 |
| X coordinate | X coordinate in standard space of region | −45 |
| Y coordinate | Y coordinate in standard space of region | 14 |
| Z coordinate | Z coordinate in standard space of region | 24 |
| Group registration atlas | (N/A, MNI, Talairach, none) | Talairach |
| Free text/notes annotation author | Additional notes, comments or description | |
| *Author | Link to individual who uploaded the information | Fws |
Table 3 shows each field in our online database, and provides a short description and an example for each. All fields are either numeric or available in dropdown menus generated from look-up tables; ‘Other’ is an option in these dropdown menus, which if selected triggers a dialog box asking user to enter a short value and value label; these additions are automatically sent to system administrator and Phenowiki project team for periodic review. Items marked with a * are required to start a record.
Separate descriptions for each effect (1 through n) in the study for applicable items in the category if necessary. Additional items will be required depending on the study design (e.g., ICC values for heritability studies or brain region for imaging study). Example values are not from a single source, as one paper would be unlikely to contain data enabling completion of all fields. More information is available online at (www.phenowiki.org).