Table 1.
Parameter (n=48) | Number of patients (%) | |
---|---|---|
Etiology | Hypoxic ischemic brain injury (n=32) | 32 (66.7) |
Diffuse hypoxic ischemic injury | 17 | |
Periventricular leukomalacia | 7 | |
Hemorrhagic infarction | 5 | |
Focal ischemic infarction | 3 | |
Central nervous system infection (n=12) | 12 (25.0) | |
Encephalitis | 9 | |
Meningitis | 3 | |
Head trauma (n=4) | 4 (8.3) | |
Epilepsy classification | Lennox-gastaut syndrome | 33 (68.8) |
Symptomatic focal epilepsy | 13 (27.1) | |
Infantile spasms | 2 (4.1) | |
Surgical procedure | Corpus callosotomy | 21 (43.8) |
Functional hemispherectomy | 15 (31.3) | |
Multilobar resection | 9 (18.8) | |
Cortisectomy | 2 (4.2) | |
Unilobar resection | 1 (2.1) | |
Mental retardation | Before epilepsy onset | 22 (43.8) |
Before surgery | 48 (100.0) | |
Past treatment history | History of Ketogenic diet | 21 (43.8) |
History of Steroid therapy | 5 (10.4) | |
Median (range: 25–75p) | ||
AEDs prior to surgery | 4,0 (3.0–4.8) | |
Age at insult (yr) | 0.4 (0.0–1.7) | |
Age at seizure onset (yr) | 2.1 (1.0–4.6) | |
Age at surgery (yr) | 9.1 (4.9–13.3) | |
Lead time from insult to epilepsy (yr) | 0.8 (0.0–3.0) | |
Epilepsy duration (yr) | 5.1 (2.2–8.1) | |
Follow up duration (yr) | 2.7 (1.8–4.5) |