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. 2014 Jan 29;144(4):425–430. doi: 10.3945/jn.113.187203

TABLE 2.

Top cytosine–phosphate–guanine methylation sites associated with n–3 PUFA intake in the study population (n = 185)1

Chromosome Position Marker Gene Genomic region Direction of association P
1 201,625,499 cg07999988 NAV1 — + <1 × 10−16
16 57,437,864 cg02050165 CCL17 — + 8 × 10−16
10 124,905,105 cg05144067 — North Shore − 5 × 10−15
3 148,804,275 cg21926402 HLTF Island − 2 × 10−14
12 133,345,809 cg07249343 GOLGA3 North Shelf + 8 × 10−14
1 12,633,465 cg05230551 DHRS3 — + 1 × 10−12
3 148,804,272 cg04836786 HLTF Island − 1 × 10−11
17 29,159,594 cg05952098 ATAD5 South Shore + 2 × 10−11
11 64,794,859 cg17101226 SNX15 Island + 3 × 10−11
6 7,313,623 cg00520393 SSR1 Island + 5 × 10−11
5 434,998 cg22951524 AHRR — + 1 × 10−10
2 171,571,716 cg06272543 SP5/LOC440925 Island − 2 × 10−10
1 182,759,062 cg15293611 — Island + 2 × 10−10
15 34,635,452 cg22686731 NOP10 — + 3 × 10−10
1 150,601,613 cg23912435 ENSA North Shore + 3 × 10−9
10 90,749,255 cg06450397 ACTA2/FAS North Shore + 4 × 10−9
2 26,101,348 cg19084174 ASXL2 Island + 5 × 10−9
3 148,804,477 cg24041269 HLTF Island − 1 × 10−8
16 31,711,872 cg16585380 C16orf67 Island + 1 × 10−8
15 40,226,279 cg21830797 EIF2AK4 Island + 2 × 10−8
9 13,284,899 cg21186560 — — + 2 × 10−8
20 331,827 cg24601011 NRSN2 South Shelf − 4 × 10−8
10 90,750,580 cg03672854 ACTA2/FAS Island + 5 × 10−8
6 21,666,569 cg10086104 FLJ22536 North Shore + 6 × 10−8
3 51,705,097 cg03855276 TEX264 Island + 6 × 10−8
1 43,855,450 cg05704639 C1orf84/MED8 Island + 6 × 10−8
16 31,153,871 cg07065683 PRSS36 Island + 8 × 10−8
1

ACTA2, actin α 2 smooth muscle; AHRR, aryl-hydrocarbon receptor repressor; ASXL2, additional sex combs-like 2; ATAD5, ATPase family AAA domain containing 5; C16orf67, C16 open reading frame 67; C1orf84, C1 open reading frame 84; CCL17, chemokine ligand 17; DHRS3, dehydrogenase/reductase SDR family member 3; EIF2AK4, eukaryotic translation initiation factor 2 α kinase 4; ENSA, endosulfine α FAS, Fas cell surface death receptor; FLJ22536, hypothetical locus LOC401237; GOLGA3, golgin A3; HLTF, helicase-like transcription factor; LOC440925, uncharacterized LOC440925; MED8, mediator complex subunit 8; NAV1, neuron navigator 1; NOP10, NOP10 ribonucleoprotein; NRSN2, neurensin 2; PRSS36, protease serine 36; SNX15, sorting nexin 15; SP5, SP5 transcription factor; SSR1, signal sequence receptor α TEX264, testis expressed 264; —, not available.