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. 2013 May 14;122(4):491–498. doi: 10.1182/blood-2013-02-453175

Table 2.

Comparison of survival after transplantation of double unit UCBT with that of adult donors

Series Patients, n Conditioning Graft source Follow-up, y Median age, y Survival (PFS or DFS), % Comment
Brunstein, Blood 2010,66 leukemia 128 Myelo UCB 5 25 51 UCB similar to MRD, MUD
204 Ablative MRD 40 33
152 MUD 31 48
52 MMUD 31 38
Ponce, BBMT 2011,67 heme malignancy 75 Myelo UCBT 2 37 55 UCB similar to MUD
108 Ablative MRD 47 66
184 MUD 48 55
Brunstein, Blood 2011,69 leukemia and lymphoma 50 RIC UCB 1 58 46 Now a randomized Clinical Trials Network study
50 haplo BM 48 48
Chen, BBMT 2012,68 hematologic malignancy 64 RIC dUCB 3 53 30 UCB similar to MUD
221 MUD 58 40

PFS, progression-free survival.