The dynamics of infection. A, The “survival curve,” indicating the fraction of uninfected patients for different age groups detected by microscopy (dashed lines), or by PCR (solid lines). Different colors indicate different age groups; C1 (1–4 years old), blue triangles and blue lines; C2 (5–9), green diamonds and green lines; C3 (10–14), orange squares and orange lines; A (>15), red circles and red lines. B, The delay between PCR and microscopy detection is indicated for each patient. Solid diamonds are patients where both PCR and microscopy measurements are present. Open diamonds are patients where only PCR detection occurs before the end of follow-up; in this case, the delay indicated is from PCR detection to the final follow-up time (week 11). Median growth rates and interquartile range are indicated. Horizontal bars above indicate groups that are significantly different (P < .05, Kruskal–Wallis test). Abbreviations: A, adults; C1, C2, C3, children of increasing age; PCR, polymerase chain reaction.