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. 2014 Mar 13;10(3):e1003509. doi: 10.1371/journal.pcbi.1003509

Figure 5. Model validation: simulation of ABCA1 and ApoA-I mutations compared with literature data for HDL-C (panel A) and ApoA-I (panel B).

Figure 5

For the simulation results, the mean and the 95% confidence intervals are plotted. The data sources are Asztalos et al [46] and Santos et al [47]; the mean ± SD are shown. The model simulations of the mutation cases were obtained by taking the parameter values for the nominal subject and set Inline graphic and Inline graphic to 50% and 0% of the nominal values respectively.