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. 2014 Mar 13;10(3):e1003509. doi: 10.1371/journal.pcbi.1003509

Figure 13. Comparison of CETP inhibition with ABCA1 up-regulation: changes in RCT rate (panel A) and biomarkers (ApoA-I, panel B; HDL size, panel C; HDL particle concentration, panel D; LDL-C, panel E) versus the rise in HDL-C.

Figure 13

The nominal subject is taken as the baseline. The model simulation of CETP inhibition is compared with literature data of CETP inhibitors, Dalcetrapib [50], Torcetrapib [51] and Anacetrapib [52].