Skip to main content
. Author manuscript; available in PMC: 2014 Mar 13.
Published in final edited form as: Pharm Res. 2009 Feb 19;26(6):1407–1418. doi: 10.1007/s11095-009-9851-0

Table II.

Cathepsin B Catalyzed Drug Release from Polymer-drug Conjugates

Time (min)
Molecule releaseda Polymer number 15 60 180
AH-GDM (%) P1 6.06±0.12 11.0±0.30 15.0±0.16
P2 7.50±0.09 15.8±0.29 22.5±0.25
Gly-AH-GDM (%) P1 10.1±0.24 19.1±0.81 21.8±0.36
P2 12.8±0.22 25.2±0.88 27.9±0.75
Total (%) P1 16.2±0.36 30.1±1.10 36.9±0.50
P2 20.3±0.32 41.0±1.15 50.4±0.92

For sample characteristics see Table I. Data represent mean ± SD (n=3)

a

As detected by RP-HPLC