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. Author manuscript; available in PMC: 2015 Mar 1.
Published in final edited form as: Nucl Med Biol. 2013 Dec 10;41(3):282–289. doi: 10.1016/j.nucmedbio.2013.12.002

Figure 6. Histology.

Figure 6

Representative samples removed at the end of the 40 day study and stained using H&E staining. Organs showed no difference compared to controls. Arrows represent potential types of evidence for radiation related effects from 90Y-HPMA copolymer-DOTA and hyperthermia treatment.

A) Heart (magnification 40×)

B) Lung (40×)

C) Liver (40×)

D) Spleen (40×)

E) Kidney (40×)

F) Radiotherapy treated tumor (40×)

G) Radiotherapy treated tumor (100×)

H) Radiotherapy treated tumor (100×)

Solid black arrow = thanatosome infiltration

White arrow = Fibrosis

Grey arrow = Vacuole formation

Striped arrow = Apoptotic bodies