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. 2014 Mar 13;9(3):e89956. doi: 10.1371/journal.pone.0089956

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© 2014 Chen et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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A. DNMT3b level was positively correlated with IL-6 expression in human oral cancer specimens (P<0.0001). Representative slides of a selected tumor specimen positively staining for both IL-6 and DNMT3b is shown at ×100 and 400 magnification. B. Survival differences according to developing disease failure or not, the positive staining of DNMT3b and positive staining for both DNMT3b and IL-6. The Kaplan- Meier overall survival curves shows that the positive groups were linked with shorter survival compared to that of respective negative group.