Table 1. Clinico-pathological characteristics of locally advanced oral cancer patients.
| No. of patients | |||
| IHC-DNMT3b (−) | IHC- DNMT3b (+) | p value | |
| patients | 49 | 76 | |
| Age | 37–77 | 31–84 | |
| > = 55 y/0 | 25 | 40 | 0.86 |
| <55 y/o | 24 | 36 | |
| Differentiation | |||
| W-D | 29 | 34 | 0.06 |
| M-D | 11 | 31 | |
| P-D | 5 | 8 | |
| Unknown | 4 | 3 | |
| Clinical stage | |||
| < = III | 25 | 34 | 0.49 |
| IV | 24 | 42 | |
| Pathologic LN metastasis | |||
| N0 | 32 | 23 | 0.001* |
| N1–3 | 17 | 53 | |
| Risk factors | |||
| No | 18 | 15 | 0.035* |
| Yes | 31 | 61 | |
| Pathology stage | |||
| III | 18 | 18 | 0.11 |
| IV | 31 | 58 | |
| Adjuvant RT | |||
| <4500 cGy | 12 | 16 | 0.65 |
| > = 4500 cGy | 37 | 60 | |
| Failure | |||
| Local-regional failure and/or distant metastasis | 6 | 40 | 0.000* |
| Disease free | 43 | 36 | |
Risk factors including extracapsular spread, the presence of preineural, vascular or lymphatic invasion.
* p value<0.05.