Table 2. Univariate analysis to determine factors associated with prognosis.

Variables	P value for Overall survival
Clinical stage	0.662
LN metastasis	0.245
Risk factor	0.74
Pathologic stage	0.74
Positive staining for DNMT3b	0.000*
Positive staining for IL-6	0.001*
Positive staining for DNMT3b and IL-6	0.000*
Disease failure	0.000*

Risk factors including extracapsular spread, the presence of preineural, vascular or lymphatic invasion.

* p value<0.05.