HDAC3 occupies the regions spanning the transcription start sites in the CDK6, NEK7, NANOS1, and RAPH1 genes.
A–D, analysis of chromatin occupancy of HDAC3 at the CDK6 (A), NEK7 (B), NANOS1 (C), and RAPH1 (D) genes in H1975 and H1792 cells by quantitative ChIP (qChIP). A diagrammatic representation of individual genes is also shown. Arrows indicate the PCR-amplified regions (a and b). TSS, transcription start site. Data are presented as the mean ± S.E. (error bars). *, p < 0.05; **, p < 0.01; ***, p < 0.001.