FIGURE 8.
Neutralization of the WT and LLP2Lys2-mutated viruses by broadly neutralizing antibodies. The 89.6 WT or LLP2Lys2 viruses were incubated for 1 h at 37 °C with the indicated concentrations of 2F5 (A), 4E10 (B), F425B4e8 (C), 2G12 (D), HIV Ig (E), IgG1b12 (F), PGT128 (G), or human IgG1κ (negative control, H) antibodies prior to infection of TZMbl cells. Luciferase activity was analyzed 48 h post-infection. The results are expressed as a percentage of neutralization and are representative of two to three separate experiments.