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. Author manuscript; available in PMC: 2015 Feb 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2013 Dec 19;34(2):346–354. doi: 10.1161/ATVBAHA.113.302848

Figure 3.

Figure 3

Chemical inhibition of palmitoylation decreases insulin-induced and VEGF-induced cell migration and in vitro tube formation. A, Representative images (3 independent experiments) from cell transwell migration assays in the presence and absence of the palmitoylation inhibitor 2-bromopalmitate (2-BP, 20 μM). B, Quantified data for cell migration. C, Cells were infected with lentiviruses then treated with vehicle or 2-BP (20 μM) followed by plating on Matrigel. Representative images (3 independent experiments) are shown in the presence of control, insulin, or VEGF. D, Quantification of tube number (relative to controls) with different interventions. E, Quantification of tube length with different interventions. *indicates P<0.05 by ANOVA.