Table 1.
Substrate | Inhibitor | UGT1A1 (μg/ml) | Reaction time (min) | ||
---|---|---|---|---|---|
| |||||
Name | Concentration(μM) | Name | Concentration (μM) | ||
3HF | |||||
7HF | 0.625, 2.5, 5, 10 | 3,7,4′THF | 0, 0.313, 0.625, 1.25, 5 | 26.54 | 30~120 |
4′HF | |||||
3HF | |||||
3,7,4′THF | 0.313, 0.625,1.25,5 | 7HF | 0, 0.625, 2.5, 5, 10 | 6.62~26.54 | 15~60 |
4′HF |