Table 1.
Baseline Demographic and Clinical Characteristics of Sample
| Exercise (N = 1158) | Usual Care (N = 1164) | ||||||
|---|---|---|---|---|---|---|---|
| N with nonmissing data | BDI-II < 14 (N=821) | BDI-II ≥ 14 (N=337) | All Exercise Participants | BDI-II < 14 (N=848) | BDI-II ≥ 14 (N=316) | All Usual Care Participants | |
| Age [Years] | 2322 | 61 (52, 69) | 56 (50, 64) | 59 (51, 68) | 61 (53, 69) | 56 (47, 63) | 59 (51, 68) |
| Race : | 2288 | ||||||
| Black | 32% (262) | 35% (115) | 33% (377) | 30% (254) | 37% (116) | 33% (377) | |
| White | 62% (503) | 59% (194) | 61% (697) | 64% (539) | 59% (184) | 61% (697) | |
| Other | 5% (43) | 7% (22) | 6% (65) | 5% (45) | 4% (11) | 6% (65) | |
| Sex : Women | 2322 | 31% (252) | 28% (94) | 30% (346) | 26% (220) | 28% (90) | 30% (346) |
| Region : US | 2322 | 88% (723) | 90% (303) | 89% (1026) | 88% (744) | 92% (292) | 89% (1026) |
| Marital Status: Married | 2315 | 59% (481) | 53% (178) | 57% (659) | 61% (513) | 52% (165) | 58% (678) |
| Education: > High School | 2271 | 63% (505) | 57% (189) | 62% (694) | 61% (500) | 51% (161) | 58% (661) |
| Income: > $25K | 2067 | 62% (460) | 52% (156) | 59% (616) | 62% (459) | 50% (144) | 59% (603) |
| BDI-II | 2322 | 6 (4, 9) | 20 (16, 25) | 8 (5, 15) | 6 (3, 9) | 20 (17, 25) | 8 (4, 15) |
| Peak VO2 [mL/kg/min] | 2268 | 15 (12, 18) | 14 (11, 17) | 14 (11, 18) | 15 (12, 18) | 14 (11, 17) | 14 (12, 18) |
| Body Mass Index [kg/m2] | 2316 | 30 (26, 34) | 31 (27, 36) | 30 (26, 35) | 29 (26, 34) | 32 (27, 37) | 30 (26, 35) |
| Diabetes | 2322 | 32% (261) | 35% (117) | 33% (378) | 30% (255) | 36% (115) | 32% (370) |
| Hypertension | 2309 | 62% (504) | 61% (207) | 62% (711) | 57% (483) | 61% (190) | 58% (673) |
| Current Smoking | 2311 | 14% (116) | 20% (68) | 16% (184) | 16% (133) | 21% (66) | 17% (199) |
| NYHA Class: III or IV | 2322 | 31% (258) | 53% (177) | 38% (435) | 32% (269) | 47% (147) | 36% (416) |
| Angina class: None | 2319 | 85% (694) | 78% (261) | 83% (955) | 87% (735) | 80% (252) | 85% (987) |
| CHF Etiology: Non-Ischemic | 2322 | 49% (399) | 48% (162) | 48% (561) | 47% (396) | 55% (173) | 49% (569) |
| LVEF | 2318 | 25 (20, 30) | 25 (20, 30) | 25 (20, 30) | 25 (20, 30) | 25 (20, 30) | 25 (20, 30) |
| Six Minute Walk [meters] | 2271 | 377 (300, 442) | 351 (279, 420) | 366 (296, 436) | 380 (310, 440) | 354 (266,) 420 | 373 (300, 432) |
| Mitral Valve Regurgitation: High | 2129 | 11% (81) | 14% (42) | 12% (123) | 11% (88) | 15% (44) | 12% (132) |
| Ventricular Conduction: Normal | 2263 | 44% (352) | 42% (137) | 43% (489) | 44% (360) | 41% (127) | 43% (487) |
| KCCQ Score | 2322 | 75 (61, 86) | 48 (37, 62) | 68 (50, 82) | 76 (61, 88)) | 48 (36, 58) | 69 (52, 84) |
| Weber Score | 2268 | 3 (2, 3) | 3 (2, 3) | 3 (2, 3) | 3 (2, 3) | 3 (2, 3) | 3 (2, 3) |
| Blood Urea Nitrogen | 2020 | 21 (16, 28) | 18 (15, 28) | 20 (15, 28) | 19 (15, 28) | 21 (15, 29) | 21 (15, 28) |
| Beta Blockade Dose [mg/day] | 2302 | 25 (13, 50) | 50 (13, 50) | 38 (13, 50) | 28 (13, 50) | 25 (13, 50) | 25 (13, 50) |
| Loop Diuretic Dose [mg/day] | 2289 | 40 (1, 80) | 40 (20, 80) | 40 (20, 80) | 40 (20, 80) | 40 (20, 80) | 40 (20, 80) |
| Any antidepressant | 2322 | 16% (131) | 35% (117) | 21% (248) | 17% (149) | 40% (129) | 23% (278) |
Values are median (25th, 75th percentile) for continuous variables and % (N) of column for categorical variables.
BDI-II: Beck Depression Inventory II
NYHA: New York Heart Association
LVEF: Left ventricular ejection fraction
KCCQ: Kansas City Cardiomyopathy Questionnaire is a 23-item survey to assess quality of life in HF patients. Higher scores reflect better quality of life.
Weber Score: Weber scores reflect levels of aerobic capacity with A (peak VO2 > 20 mL/kg/min); B (peak VO2 > 16 and ≤ 20); C (peak VO2 > 10 and ≤ 16); D (peak VO2 ≤ 10).