Table 1.
Effect of different extracts of Gentiana kurroo Royle at a dose of 250 mg/kg on Carrageenan-induced paw edema in rats (mean ± S.E) (n = 4).
| Serial number | Groups | Dose (mg/kg) | Initial paw volume (mL) |
Paw volume after 4 h (mL) |
Edema (4 h) | % age inhibition (4 h) |
|---|---|---|---|---|---|---|
| 1 | Control | NS | 2.07 ± 0.075 | 1.02 ± 0.048 | 1.05 ± 0.029a | — |
| 2 | GMT | 250 | 1.55 ± 0.029 | 1 ± 0.041 | 0.55 ± 0.029b | 47.62 |
| 3 | GET | 250 | 1.8 ± 0.071 | 1 ± 0.041 | 0.8 ± 0.071ac | 23.81 |
| 4 | GPT | 250 | 1.95 ± 0.056 | 0.97 ± 0.041 | 0.97 ± 0.074bc | 7.62 |
| 5 | GAQ | 250 | 1.72 ± 0.025 | 0.97 ± 0.025 | 0.75 ± 0.029b | 28.57 |
| 6 | Diclo | 20 | 1.57 ± 0.025 | 1.1 ± 0.041 | 0.47 ± 0.025c | 55.24 |
Values along the same column with different superscripts are statistically significant to each other using Tukey's HSD test (P < 0.05). GMT: methanolic extract; GET: ethyl acetate extract; GPT: petroleum ether extract; GAQ: aqueous extract; Diclo: diclofenac.