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. 2014 Mar 13;9(3):e91606. doi: 10.1371/journal.pone.0091606

Figure 5. The switch from PKM2 to PKM1 by OA results from the decrease in Myc, hnRNPA1 and hnRNPA2 expression.

Figure 5

(A) The expression of c-Myc, hnRNPA1 and hnRNPA2 was determined by immunoblot analysis in PC-3 and MCF-7 cells treated with 50 or 100 µg/ml OA for 6 or 12 hr respectively. (B) The expressionof c-Myc, hnRNPA1 and hnRNPA2 expression was determined by immunoblot analysis in PC-3 cells treated with OA (100 µg/ml) or/and MHY1485 (2 µM) respectively. (C) The level of c-Myc, hnRNPA1, hnRNPA2, PKM1 and PKM2 was determined by immunoblot assays in PC-3 cells treated with plasmids pMXs-hcMYC (Flag-cMyc) in the presence or absence of OA. β-tubulin was used as endogenous references.