Table 5. SNPs located in the two CNVs regions or outside the two CNVs boundaries and their association signals with ALM.

CNV region	Chr	SNP	Position	Discovery sample			Replication sample
				Allele	MAF	p-value	Allele	MAF	p-value
CNV1191	7	rs6969250	149,923,478	C/T	0.23	NA	C/T	0.17	NA
	7	rs11984138	149,931,668	G/A	0.24	0.77	G/A	0.33	0.9
	7	rs10271154	150,413,004	C/T	0.25	0.82	C/T	0.37	0.46
	7	rs4725388	150,413,550	G/A	0.28	NA	G/A	0.55	NA
	7	rs13239507	150,415,340	T/C	0.28	NA	T/C	0.42	NA
	7	rs6464126	150,416,254	C/T	0.28	NA	C/T	0.42	NA
	7	rs11769150	150,416,686	C/T	0.18	0.82	C/T	0.14	0.02
	7	rs10270107	150,417,979	G/A	0.26	NA	G/A	0.35	NA
	7	rs6957724	150,419,237	C/T	0.24	NA	C/T	0.12	NA
	7	rs11773852	150,421,052	C/T	0.25	0.63	C/T	0.22	0.98
CNV2580	22	rs4820470	41,236,248	A/G	0.15	NA	A/G	0.05	-
	22	rs12485160	41,237,563	C/T	0.13	NA	C/T	0.11	NA
	22	rs5758786	41,256,609	A/A	0	–	A/G	0.02	–
	22	rs4822160	41,262,261	A/G	0.20	0.56	A/G	0.19	0.99
	22	rs9614207	42,898,768	A/G	0.42	NA	A/G	0.23	NA
	22	rs9614208	42,899,411	G/A	0.41	0.67	G/A	0.14	0.34
	22	rs7292425	42,900,747	C/A	0.18	NA	C/A	0.34	NA
	22	rs139107	42,901,313	G/A	0.14	NA	G/A	0.16	NA
	22	rs9614362	42,903,911	G/A	0.30	0.96	G/A	0.13	0.46
	22	rs12483834	42,904,365	C/G	0.02	0.67	C/G	0.16	0.37
	22	rs139116	42,904,875	T/C	0.36	0.28	T/C	0.20	0.02
	22	rs2092351	42,905,737	G/A	0.36	0.31	G/A	0.33	0.18
	22	rs139120	42,905,880	G/A	0.34	0.32	G/A	0.17	0.02
	22	rs878406	42,906,306	A/T	0.02	0.82	A/T	0.19	0.32
	22	rs3747208	42,907,201	A/G	0.10	NA	A/G	0.08	–
	22	rs139123	42,907,418	G/A	0.37	NA	G/A	0.36	NA
	22	rs139124	42,907,465	G/A	0.34	NA	G/A	0.15	NA
	22	rs7287117	42,907,988	G/A	0.02	–	G/A	0.18	NA
	22	rs9306473	42,908,483	G/A	0.002	–	G/A	0	–

Notes:

NA: the failure of passing the quality control procedure (QC).

–: not available due to low minor allele frequency.

Chr: chromosome.

MAF: minor allele frequency.