Table 2.
The pharmacokinetic parameters of (4E,6E,12E)-tetradecatriene-8,10-diyne-1,3-diyl diacetate of raw and processed AtractylodisRhizoma at a dose of 40 g·kg−1 to rats, respectively (n = 6).
| Parameters | Raw | Processed |
|---|---|---|
| AUC(0-t) (mg·h·L−1) | 0.260 ± 0.137 | 0.265 ± 0.100 |
| AUC(0-∞) (mg·h·L−1) | 0.317 ± 0.157 | 0.303 ± 0.111 |
| MRT(0-t) (h ) | 7.706 ± 0.888 | 7.384 ± 0.86 |
| MRT(0-t) (h) | 14.86 ± 6.813 | 12.22 ± 3.364 |
| t 1/2z (h) | 9.905 ± 7.382 | 8.047 ± 3.347 |
| T max (h) | 2.333 ± 0.816 | 1.000 ± 0.817 |
| C max (mg·L−1) | 0.038 ± 0.024 | 0.042 ± 0.017 |