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Inhibition of hematopoietic progenitor colony formation from healthy volunteers and polycythemia patients
| Healthy controls (n = 3) | PV (n = 3) | PV without cytokine (n = 3) | |
|---|---|---|---|
| BFU-E IC50, nM | 407 | 223 | 67 |
| CFU-M IC50, nM | 551 | 444 | ND |
BFU-E indicates burst forming unit-erythroid; CFU-M, colony forming unit-myeloid; and PV, polycythemia vera.
