Table 1.

Applications of computerized decision support in adult, pediatric and neonatal critical care

Type of support tool	Example or subject
Adult critical care
Diagnostic	DXplain[28]
	Mortality and length of stay prediction[9,29]
Alert and reminder	Ventilator induced lung injury[84]
	Blood pressure variability while on vasopressors[32]
	Adverse drug reactions[19]
	Drug induced thrombocytopenia[30]
	Epidural hematoma with neuraxial anesthesia[31]
Protocol/procedure	Acute respiratory distress syndrome[33-35]
	Sepsis[21]
	VTE prophylaxis and events in trauma patients[37]
	VTE prophylaxis[38,39]
	Tidal volume during mechanical ventilation[36]
Management	Ventilator fraction of inspired oxygen[41]
	Pressure support ventilation[42]
	Antibiotic recommendation[43,44]
	Blood glucose control[46-48]
	Sepsis[21]
	Heparin dosing after myocardial infarction[45]
Research	Mortality prediction[29]
	Prediction of fluid requirement[53]
	Predictive alerts for hemodynamic instability[49-51]
	Ventilator settings[76]
	Prediction of dialysis need[52]
	Insulin e-protocol[54,85]
Pediatric and neonatal critical care
Diagnostic	ISABEL (www.isabelhealthcare.com)[59,86]
	SimulConsult (www.simulconsult.com)[87]
	MEDITEL pediatric diagnostic system[58]
	Outcome prediction and severity of illness[55-57]
Alert and Reminder	Drug interaction[62]
	Prescription errors and adverse drug events[18,61]
	Parenteral nutrition orders[61]
	NICU pulse oximeter[60]
Protocol/Procedure	Blood transfusions[63]
	Medications[61]
	Parenteral nutrition[64]
Management	Oxygen in ventilated newborns[68]
	Antibiotic recommendation[44,65]
	Blood glucose control[69]
	Medication information databases[88]
	Medication dosing calculators[61]
	Ventilator management in neonates[66,67]
Research	Virtual PICU (www.picu.net)[89]
	Pediatric cardiac care consortium[70]
	Acuity scoring systems for quality improvement[56,57]
	Ventilator settings in neonates[71]
	Neonatal seizure detection[72]
	Glycemic control[90]

VTE: Venous thromboembolism; PICU: Pediatric intensive care unit; NICU: Neonatal intensive care unit.