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. 2012 Nov 29;7(1):500–512. doi: 10.1021/nn3046055

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In vitro MRI studies of PEG(5)-BP-USPIO: (A) Plot of the relaxation rates (R1= 1/T1) as a function of Fe concentration showing the r₁ relaxivities of PEG(5)-BP-USPIO (black circles, 9.5 mM^–1 s^–1) and Feraspin XS (gray triangles, 5.4 mM^–1 s^–1); (B) Phantom MRI images (grayscale, left; color scale, right) of PEG(5)-BP-USPIO showing the concentration-dependent effect in T1- (top) and T2- (bottom) weighted sequences. The arrow indicates the most concentrated vial (5.3 mM Fe) and the concentration decreases anticlockwise, with the last vial containing water only.