Table 1. USPIOs and Corresponding Nanoparticle Size by TEM, DLS, Nature of the Coating and Relaxation Properties at 3 T. The Entries Have Been Ordered by Increasing r2/r1 Ratio.
| USPIO | DTEM (nm) | DH (nm) | coating | r1 (mM-1 s-1) | r2 (mM-1 s-1) | r2/r1 | medium | T (°C) | ref |
|---|---|---|---|---|---|---|---|---|---|
| PEG(5)-BP-USPIOs | 5.5 | 23 | PEG-BP | 9.5 | 28.2 | 2.97 | H2O | RT | this work |
| ESION | 2.2 | PEG-PO | 4.8 | 17.5 | 3.65 | H2O | ref (19) | ||
| VSOP-C184 | 8.6 | 19 | citrate | 8.0 | 34.0 | 4.25 | H2O | 37 | ref (8) |
| ESION | 3 | 15 | PEG-PO | 4.8 | 29.2 | 6.08 | H2O | ref (19) | |
| Feraspin XS | 18 | carboxydextran | 5.4 | 36.3 | 6.72 | H2O | RT | this work | |
| Ferucarbotran (Supravist) | 3–5 | 21 | carboxydextran | 7.3 | 57.0 | 7.81 | H2O | 37 | ref (51), (52) |
| Ferumoxytol (C7228) | 6.7 | 35 | carboxymethyldextran | 7.5 | 92.0 | 12.27 | H2O | 37 | ref (8) |
| Ferrumoxtran-10 (Sinerem) | 4.5 | 34 | dextran + citrate | 5.0 | 66.0 | 13.20 | H2O | 37 | ref (46), (48) |
| ESION | 12 | - | PEG-PO | 2.4 | 58.8 | 24.50 | H2O | - | ref (19) |