Figure 7. Odor-evoked intrinsic signals are independent of change in breathing frequency.
(A) Single trial map of the amyl acetate-evoked activity reported by IOS when the mouse is breathing at 1.8 (left) and 3 Hz (right). LUT: −0.003 to 0.003. The respiration pattern recorded during each trial is shown below each image (I: inspiration, E: expiration); the light gray vertical bar represents odor presentation (5 s). (B) Average values of glomerular response amplitude (ΔR/R) at 1.8 Hz, plotted against amplitudes at 3 Hz (Wilcoxon signed-rank test, n = 104 glomeruli from three mice, p=0.2945). (C) Average values of glomerular response amplitude at different breathing frequencies (2, 2.2, 2.4, 2.6, 2.8 and 3 Hz). Values are normalized relative to responses recorded at 1.8 Hz (Repeated measure one-way ANOVA, n = 3 mice, F = 0.4499, p=0.6505). Values are represented as mean ± SEM.