Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2014 Mar 14;8:19. doi: 10.3389/fncir.2014.00019

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2014 Fischl and Burger.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Pre-application of glycine suppresses evoked IPSC trains in the SON. (A) Schematic of the recording arrangement. (B) Representative trace from an E18 SON neuron during the 10 s glycine application. (C) Expanded view of the dashed box in (B) showing evoked responses. (Ci) Evoked responses in control, strychnine, and washout conditions with no glycine pre-application. (Cii) Evoked IPSCs following the glycine pre-application show amplitude suppression that is blocked by strychnine. (D) Population data values for the IPSC amplitudes in each condition (* indicates significant difference, p < 0.01). (E) Ratio of evoked amplitudes between glycine pre-application and no glycine in each condition reveals a decrease in the suppression (ratio near 1) in strychnine.