Table 3.
Survival Models of Abuse/Dependence
| Nicotine | Cannabis | Cocaine | Alcohol | |||||
|---|---|---|---|---|---|---|---|---|
| HR | 95% CI | HR | 95% CI | HR | 95% CI | HR | 95% CI | |
| Inattention trajectories | ||||||||
| Medium | 1.61*** | 1.30–2.01 | 0.85 | 0.57–1.27 | 1.18 | 0.47–2.94 | 0.90 | 0.65–1.25 |
| High | 1.94*** | 1.49–2.51 | 0.74 | 0.46–1.2 | 0.82 | 0.27–2.44 | 0.92 | 0.62–1.36 |
| Hyperactivity trajectories | ||||||||
| High mother only | 0.83† | 0.68–1.02 | 0.95 | 0.65–1.39 | 1.23 | 0.53–2.86 | 0.98 | 0.72–1.34 |
| High | 0.81 | 0.62–1.06 | 1.07 | 0.66–1.73 | 1.60 | 0.57–4.47 | 0.97 | 0.65–1.46 |
| Opposition trajectories | ||||||||
| High mother only | 1.24* | 1.01–1.52 | 1.96*** | 1.32–2.9 | 1.86 | 0.74–4.66 | 1.35† | 0.99–1.86 |
| High | 1.47** | 1.14–1.88 | 2.21** | 1.37–3.57 | 2.92* | 1.05–8.14 | 1.39 | 0.94–2.06 |
| Anxiety trajectories | ||||||||
| High mother only | 0.94 | 0.77–1.15 | 0.86 | 0.6–1.24 | 0.90 | 0.39–2.05 | 0.82 | 0.60–1.11 |
| High | 0.81† | 0.65–1.02 | 0.74 | 0.47–1.17 | 1.25 | 0.54–2.87 | 0.73 | 0.51–1.06 |
| Adversity | 1.36† | 0.98–1.89 | 0.72 | 0.38–1.36 | 5.1** | 1.61–16.17 | 1.23 | 0.74–2.02 |
| Sex | 0.78** | 0.65–0.93 | 2.01*** | 1.44–2.8 | 0.74 | 0.37–1.50 | 2.15*** | 1.63–2.83 |
Note. The table presents Hazard Ratios (HR) and 95% Confidence Interval (CI) from Cox models. The time variable is the age at first symptom for each outcome as reported by the young adult at the time of diagnosis. Analyses were conducted on the 1798 participants with data for behavioral trajectories and diagnosis.
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