Figure 1.

A homozygous frameshift deletion in exon 2 of Gpr84. The mouse Gpr84 gene is located in chromosome 15: 103 308 236–103 310 438bp (ideogram, cytogenetic band F3) and contains 2 exons (Mouse Genome Build 37). The chromatograms are showing wild-type (WT) and mutant partial sequences from exon 2 obtained from C57BL/6J and DBA/2J, respectively. The 2-bp deletion is located at 103 308 576bp and generates a premature stop codon and a predicted truncated protein lacking transmembrane domains 4–7. Abbreviations: C = cytosine; T = thymine.