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. Author manuscript; available in PMC: 2014 Dec 1.
Published in final edited form as: Drug Alcohol Depend. 2013 Sep 2;133(2):693–703. doi: 10.1016/j.drugalcdep.2013.08.021

Figure 2. l-ICP acts as a partial agonist at (A1, A2) the dopamine D1 and (B) D5 receptors.

Figure 2

(A1, A2) dopamine- and l-ICP-stimulated cAMP formation in HEK cells expressing a (A1) high or (A2) moderate level of the D1 receptor were performed with different doses and dose-response curves of dopamine and l-ICP were generated. Potencies (EC50) and efficacies (Emax) of l-ICP were determined and shown in Table 2. (B). Dose-response curves of dopamine and l-ICP in stimulating cAMP formation in HEK cells expressing the D5R were generated. EC50 and Emax of l-ICP were shown in Table 2. Each value represents mean ± s.e.m. of three experiments performed in duplicate.