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. Author manuscript; available in PMC: 2014 Dec 1.
Published in final edited form as: Drug Alcohol Depend. 2013 Sep 2;133(2):693–703. doi: 10.1016/j.drugalcdep.2013.08.021

Figure 5. Effects of l-ICP on cocaine-induced hyperactivity in mice.

Figure 5

CD-1 mice were habituated to activity chambers for 50 min, pretreated with vehicle or l-ICP (1, 3 and 10 mg/kg, i.p.) for 10 min followed by saline or cocaine (20 mg/kg, i.p.) as described in Methods. Areas under curves (AUCs) were calculated for (A) total activity, (B) ambulatory activity and (C) repetitive non-ambulatory activity. Each value represents mean ± s.e.m (n=16 for veh/saline, n= 10 for all other groups).

**P<0.01, ***P<0.001, compared with the veh/cocaine group; +++P<0.001, +P<0.05 compared with veh/saline, both by two-way ANOVA followed by Bonferroni post hoc test.