Table 1. K_i values (nM) of l-ICP or l-THP binding to the human DA D1, D2, D3, D4 and D5 receptors stably expressed in HEK293 cells.

Competitive inhibition by l-ICP or l-THP of [³H]SCH23,390 binding to D1 and D5 receptors and [³H]N-Methyl-spiperone binding to D2, D3 and D4 receptors was conducted and its K_i values were determined. Each value represents mean ± s.e.m. of three experiments performed in duplicate. H, M and L represent D1R high, moderate and low expression, respectively.

	D1			D2	D3	D4	D5
	H	M	L	D2	D3	D4	D5

l-ICP	6.2±0.1	5.1±1.3	5.3±0.6	41.8±1.8	37.3±3.4	77.4±17.5	9.5±1.4

l-THP	153 ± 8.8	-	-	1125 ± 97	1371 ± 212	>1,000	305 ± 65

Table 1. Ki values (nM) of l-ICP or l-THP binding to the human DA D1, D2, D3, D4 and D5 receptors stably expressed in HEK293 cells.

Table 1. K_i values (nM) of l-ICP or l-THP binding to the human DA D1, D2, D3, D4 and D5 receptors stably expressed in HEK293 cells.