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. 2013 Oct 24;16(4):423–429. doi: 10.1093/ntr/ntt165

Table 2.

Results Showing Relationship Between Baseline Dependence Measures and Relapse by Stop-Smoking Medication Use

Predicting relapse risk over different quit periods among daily smokers who made a quit attempt, HR (95% CI)
1–7 8–14 15–30 31–90 91–180 181–270 271–420 421–730
Dependence measures
 HSI: med users 1.12 (1.08–1.18)*** 1.11 (1.04–1.19)** 1.04 (0.98–1.11) 1.00 (0.95–1.06) 1.07 (0.99–1.16) 0.88 (0.77–0.99)* 1.03 (0.87–1.22) 0.95 (0.73–1.24)
 HSI: med nonusers 1.26 (1.22–1.30)*** 1.09 (1.04–1.15)*** 1.11 (1.06–1.17)*** 1.01 (0.96–1.06) 0.98 (0.92–1.05) 0.93 (0.84–1.03) 1.02 (0.92–1.15) 1.07 (0.91–1.27)
 CPD: med users 1.20 (1.11–1.29)*** 1.10 (0.97–1.24) 1.11 (0.99–1.24) 0.99 (0.89–1.11) 1.16 (1.01–1.32)* 0.78 (0.61–0.99)* 0.89 (0.63–1.27) 0.82 (0.49–1.37)
 CPD: med nonusers 1.37 (1.29–1.45)*** 1.16 (1.06–1.28)** 1.15 (1.04–1.28)** 0.96 (0.87–1.06) 0.93 (0.81–1.07) 0.90 (0.73–1.12) 1.05 (0.83–1.32) 1.24 (0.92–1.66)
 TTFC: med users 1.17 (1.09–1.26)*** 1.22 (1.09–1.38)** 1.01 (0.91–1.12) 1.02 (0.93–1.11) 1.06 (0.94–1.19) 0.87 (0.72–1.06) 1.17 (0.90–1.53) 1.00 (0.66–1.53)
 TTFC: med nonusers 1.43 (1.36–1.50)*** 1.13 (1.04–1.22)** 1.17 (1.08–1.27)*** 1.04 (0.96–1.12) 0.99 (0.89–1.09) 0.89 (0.76–1.03) 1.02 (0.85–1.22) 1.03 (0.77–1.36)

Note. CPD = cigarette per day; HR = hazard ratios were adjusted for age, sex, income, education, country, survey year, and year of recruitment; HSI = Heaviness of Smoking Index; med = medication; TTFC = time to first cigarette upon waking.

*p < .05; **p < .01; ***p < .001.