Prevalence of intra-amniotic inflammation (Panel A) and histologic acute chorioamnionitis (Panel B) according to the results of PCR/ESI-MS and amniotic fluid cultures. Intra-amniotic inflammation was diagnosed in 70% (n=7/10) and 94% (n=16/17) of patients with positive AF culture and positive PCR/ESI-MS (≥17 GE/well) results, respectively. Patients with positive PCR/ESI-MS (GE/well ≥ 17) and negative AF culture have a prevalence of histological acute chorioamnionitis of 70% (7/10). In contrast, the prevalence of histological acute chorioamnionitis in patients with negative AF culture and negative PCR/ESI-MS (GE/well < 17) was 35% (39/112).
Prevalence of intra-amniotic inflammation and histologic acute chorioamnionitis by PCR/ESI-MS and amniotic fluid culture results
PCR: polymerase chain reaction; ESI-MS: electrospray ionization mass spectrometry.