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. Author manuscript; available in PMC: 2015 Apr 1.
Published in final edited form as: Blood Cells Mol Dis. 2013 Dec 2;52(4):195–202. doi: 10.1016/j.bcmd.2013.11.003

Table 7.

Summary of RHD/RHCE haplotype combinations found in random AA sample populations tested

Haplotype Blood donors Patients with SCD
RHD*D-RHCE*ceS homozygousa 15 4
RHD hetero/ceS homozygousa 4 0
RHD hetero/(C)ceS homozygousa 1 0
RHD hetero/RHCE*(C)ceS/ceSa 2 2
RHCE variant/RHCE*cEa 14 8
RHCE*ce254G homozygousa 2 0
RHD variant /RHD*ΨD a 51 2
Homozygous ‘common’a 4b 8c
Heterozygote 315 (69.2%) 120 (81.6%)
Total number of samples 455 147
a

patients with these haplotypes can produce alloantibodies to antigens absent from, and to partial Rh antigens on, their RBCs

b

RHD*D-RHCE*Ce (n = 15), RHD*D-RHCE*ce (n = 21), and RHD*D-RHCE*cE (n = 5)

c

RHD*D-RHCE*Ce (n = 5), RHD*D-RHCE*ce (n = 2), and RHD*D-RHCE*cE (n = 1)