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. 2014 Mar 4;171(6):1448–1461. doi: 10.1111/bph.12545

Table 1.

Levels of inflammatory mediators (pg·mL−1) in extracts of the iris and ciliary body

Control LPS LPS + HU308 LPS + AM630 LPS + AM630 + HU308
TNF-α 5.9 ± 4.1* 52.6 ± 18.12+ 0.82 ± 0.6* 16.8 ± 7.1* 5.9 ± 4.2*
IL-1β 264.2 ± 71.4* 5572 ± 1076+ 603 ± 214* 3564 ± 1453+ 550 ± 137*
IL-6 8.9 ± 2.2* 32.9 ± 5.1+ 7.5 ± 2.3* 16.5 ± 3.7* 7.2 ± 2.3*
IL-10 11.1 ± 1.8 18 ± 1.5 6.9 ± 1.3* 14.2 ± 3.0 12.9 ± 2.7
IFN-γ 1.3 ± 0.4 2.5 ± 3.8 0.8 ± 0.4* 1.4 ± 0.4 1.2 ± 0.6
CCL5 53.2 ± 17.9* 289 ± 49+ 66.2 ± 17.1* 192 ± 57.3+ 51.1 ± 13.2*
CXCL2 101 ± 34.6* 2023 ± 418+ 213 ± 58.7* 852 ± 362* 288 ± 102*
sVCAM 214 ± 34.3 363 ± 50.5 191 ± 27.1 360 ± 82 244 ± 43.4
ICAM 1304 ± 234 2118 ± 368 1208 ± 116 2333 ± 557 1589 ± 271

Data shown (mean ± SEM) are from control, LPS and LPS with treatments with CB receptor ligands: CB2 receptor agonist, HU308, CB2 receptor antagonist AM630 and combination of AM630 + HU308, n = 8–11,P < 0.05 to control, *P < 0.05 compared with LPS.